Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945095 | 0.85 | FAAH (0.43) | FAAHKMT2AMEN1MAPTHPGD | |
| SCHEMBL8945395 | 0.81 | FAAH (0.46) | ACHEFAAHMGLLKMT2AMAPT | |
| SCHEMBL8944960 | 0.76 | FAAH (0.45) | ACHEFAAHMGLLKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8945101 | 0.75 | FAAH (0.49) | ACHEFAAHMGLLKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8945510 | 0.75 | FAAH (0.44) | ACHEFAAHMGLLKMT2AMEN1 | |
| SCHEMBL8945301 | 0.75 | FAAH (0.44) | ACHEFAAHMGLLKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL8945261 | 0.75 | FAAH (0.44) | ACHEFAAHMGLLKMT2AMEN1 | |
| SCHEMBL8945200 | 0.73 | FAAH (0.50) | ACHEFAAHMGLLSSTR4RAB9A | |
| SCHEMBL8945307 | 0.73 | FAAH (0.57) | ACHEFAAHMGLLSSTR4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8945364 | 0.73 | FAAH (0.42) | ACHEFAAHMGLLMAPTSSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |