Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945049 | 0.85 | ACHE (0.40) | FAAHHPGDTSHRNPC1SMN1; SMN2 | |
| SCHEMBL8945144 | 0.83 | FAAH (0.50) | FAAHHPGDTSHRSMN1; SMN2KMT2A | |
| SCHEMBL8945066 | 0.78 | FAAH (0.48) | FAAHHPGDTSHRSMN1; SMN2KMT2A | |
| SCHEMBL8945107 | 0.78 | FAAH (0.49) | FAAHHPGDTSHRSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL8945297 | 0.77 | FAAH (0.47) | FAAHHPGDTSHRSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL8945060 | 0.77 | FAAH (0.48) | FAAHHPGDTSHRSMN1; SMN2KMT2A | |
| SCHEMBL8944953 | 0.77 | FAAH (0.48) | FAAHHPGDTSHRSMN1; SMN2KMT2A | |
| SCHEMBL8945126 | 0.76 | FAAH (0.48) | FAAHHPGDSMN1; SMN2KMT2AMAPT | |
| SCHEMBL8945327 | 0.76 | FAAH (0.45) | FAAHHPGDTSHRLMNASMN1; SMN2 | |
| SCHEMBL8945123 | 0.76 | FAAH (0.48) | FAAHHPGDTSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |