Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8945351 | 0.84 | FAAH (0.34) | FAAHSYK | |
| SCHEMBL8945077 | 0.84 | MAPT (0.43) | FAAHMGLLS1PR1 | |
| Hydrochloric Acid SCHEMBL8944982 | 0.82 | MAPT (0.42) | FAAHMGLLS1PR1 | |
| SCHEMBL8945050 | 0.82 | KCNA5 (0.37) | — | |
| SCHEMBL8945066 | 0.81 | FAAH (0.48) | FAAHMGLLS1PR1 | |
| Hydrochloric Acid SCHEMBL8945297 | 0.80 | FAAH (0.47) | FAAHMGLLS1PR1 | |
| Hydrochloric Acid SCHEMBL5618087 | 0.77 | FAAH (0.41) | FAAHMGLLAPP | |
| Hydrochloric Acid SCHEMBL8945101 | 0.77 | FAAH (0.49) | FAAHMGLL | |
| Hydrochloric Acid SCHEMBL8945078 | 0.72 | ESR1 (0.41) | FAAHMGLLSYK | |
| SCHEMBL8945159 | 0.71 | FAAH (0.35) | FAAHMGLLSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |