Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945100 | 0.86 | FAAH (0.39) | GAAALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL8945077 | 0.86 | MAPT (0.43) | MAPTPOLBHTTTP53LMNA | |
| Hydrochloric Acid SCHEMBL8944982 | 0.85 | MAPT (0.42) | MAPTPOLBHTTTP53LMNA | |
| SCHEMBL8945066 | 0.83 | FAAH (0.48) | KCNH2ALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL8945083 | 0.82 | FAAH (0.33) | — | |
| Hydrochloric Acid SCHEMBL8945297 | 0.82 | FAAH (0.47) | KCNH2ALDH1A1SMN1; SMN2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8945101 | 0.79 | FAAH (0.49) | KCNH2SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL5617796 | 0.77 | FAAH (0.43) | GAAALDH1A1SMN1; SMN2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL6991179 | 0.76 | FAAH (0.43) | GAAALDH1A1SMN1; SMN2KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL8945078 | 0.74 | ESR1 (0.41) | ALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |