Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8944982 | 0.99 | MAPT (0.42) | MAPTTP53POLBLMNAFAAH | |
| SCHEMBL8945050 | 0.86 | KCNA5 (0.37) | MAPTTP53POLBLMNAHTT | |
| SCHEMBL8945166 | 0.86 | MAPT (0.39) | MAPTTP53POLBLMNAFAAH | |
| SCHEMBL8945066 | 0.84 | FAAH (0.48) | MAPTTP53FAAHMGLLKMT2A | |
| SCHEMBL8945083 | 0.84 | FAAH (0.33) | FAAHMGLLS1PR1 | |
| Hydrochloric Acid SCHEMBL8945297 | 0.83 | FAAH (0.47) | MAPTTP53FAAHMGLLKMT2A | |
| Hydrochloric Acid SCHEMBL8945101 | 0.80 | FAAH (0.49) | TP53LMNAFAAHMGLLMEN1 | |
| SCHEMBL5617540 | 0.76 | MAPT (0.44) | MAPTTP53POLBLMNAFAAH | |
| SCHEMBL2968296 | 0.76 | MAPT (0.47) | MAPTTP53POLBLMNAFAAH | |
| Hydrochloric Acid SCHEMBL8945078 | 0.75 | ESR1 (0.41) | POLBFAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |