Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945093 | 0.90 | FAAH (0.41) | MAPTTP53SPHK1SSTR4BRD4 | |
| SCHEMBL30308963 | 0.80 | HTT (0.41) | MAPTPOLBSPHK1BRD4HSD11B2 | |
| SCHEMBL22116166 | 0.80 | HTT (0.41) | MAPTPOLBSPHK1BRD4HSD11B2 | |
| SCHEMBL31752274 | 0.76 | SPHK1 (0.38) | SPHK1BRD4HSD11B2 | |
| SCHEMBL3612721 | 0.74 | SPHK1 (0.44) | SPHK1BRD4HSD11B2 | |
| SCHEMBL19357528 | 0.74 | SPHK1 (0.44) | SPHK1BRD4HSD11B2 | |
| SCHEMBL3612715 | 0.74 | SPHK1 (0.44) | SPHK1BRD4HSD11B2 | |
| SCHEMBL4346836 | 0.74 | SPHK1 (0.40) | MAPTSPHK1BRD4HSD11B2 | |
| SCHEMBL4346843 | 0.74 | SPHK1 (0.40) | MAPTSPHK1BRD4HSD11B2 | |
| SCHEMBL2669188 | 0.74 | SPHK1 (0.40) | MAPTSPHK1BRD4HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |