Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.30 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31751371 | 0.95 | HSD11B2 (0.35) | SPHK1HSD11B2BRD4EPHA2PIK3CD | |
| SCHEMBL31751249 | 0.80 | HSD11B2 (0.35) | SPHK1HSD11B2BRD4 | |
| SCHEMBL24613291 | 0.78 | SPHK1 (0.43) | SPHK1HSD11B2BRD4GPR119RORC | |
| SCHEMBL26964224 | 0.78 | SPHK1 (0.43) | SPHK1HSD11B2BRD4GPR119RORC | |
| SCHEMBL15209132 | 0.77 | SPHK1 (0.48) | SPHK1HSD11B2BRD4 | |
| SCHEMBL15209134 | 0.77 | SPHK1 (0.48) | SPHK1HSD11B2BRD4 | |
| SCHEMBL8945204 | 0.76 | HTR2C (0.38) | SPHK1HSD11B2BRD4 | |
| SCHEMBL8945093 | 0.76 | FAAH (0.41) | SPHK1HSD11B2BRD4EPHA2 | |
| SCHEMBL19357528 | 0.76 | SPHK1 (0.44) | SPHK1HSD11B2BRD4GPR119 | |
| SCHEMBL3612721 | 0.76 | SPHK1 (0.44) | SPHK1HSD11B2BRD4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264954-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2025-12-26 | — | — | WO | disclosed |