Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945277 | 0.88 | KMT2A (0.40) | FAAHMGLLSSTR4SCN4AACHE | |
| SCHEMBL8945444 | 0.85 | FAAH (0.47) | FAAHSCN4ASMN1; SMN2TP53MAPT | |
| Hydrochloric Acid SCHEMBL8945073 | 0.84 | FAAH (0.47) | FAAHSCN4ASMN1; SMN2TP53MAPT | |
| SCHEMBL8945343 | 0.83 | FAAH (0.47) | FAAHMGLLSCN4AACHESMN1; SMN2 | |
| SCHEMBL8945130 | 0.83 | FAAH (0.46) | FAAHMGLLSSTR4SCN4AACHE | |
| SCHEMBL8945137 | 0.83 | SCN4A (0.50) | FAAHMGLLSCN4AACHECA12 | |
| SCHEMBL8945366 | 0.78 | FAAH (0.46) | FAAHMGLLSSTR4SCN4AACHE | |
| SCHEMBL8944960 | 0.77 | FAAH (0.45) | FAAHMGLLSSTR4ACHESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8945261 | 0.76 | FAAH (0.44) | FAAHMGLLSSTR4ACHESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8945510 | 0.76 | FAAH (0.44) | FAAHMGLLSSTR4ACHESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |