Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 7/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944992 | 0.87 | FAAH (0.44) | FAAHMGLLHIF1ASCN4A | |
| SCHEMBL8945137 | 0.87 | SCN4A (0.50) | FAAHMGLLSCN4AACHE | |
| SCHEMBL8945130 | 0.85 | FAAH (0.46) | FAAHMGLLSCN4AACHENQO1 | |
| SCHEMBL8945013 | 0.84 | FAAH (0.44) | FAAHMAPTSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL8945366 | 0.84 | FAAH (0.46) | FAAHMGLLMAPTHIF1ASMN1; SMN2 | |
| SCHEMBL8945162 | 0.83 | FAAH (0.41) | FAAHMGLLTP53MAPTHIF1A | |
| SCHEMBL8945016 | 0.78 | FAAH (0.56) | FAAHMGLLCYP1A2CYP2D6SCN4A | |
| SCHEMBL8945218 | 0.78 | FAAH (0.44) | FAAHMGLLSMN1; SMN2SCN4AACHE | |
| SCHEMBL8945017 | 0.77 | FAAH (0.43) | FAAHMGLLSMN1; SMN2SCN4AACHE | |
| Hydrochloric Acid SCHEMBL8945355 | 0.76 | FAAH (0.55) | FAAHMGLLTP53MAPTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |