Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 9/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945137 | 0.86 | SCN4A (0.50) | FAAHMGLLACHESCN4ACA12 | |
| SCHEMBL8945343 | 0.84 | FAAH (0.47) | FAAHMGLLHIF1AACHESCN4A | |
| SCHEMBL8945141 | 0.84 | FAAH (0.47) | FAAHSCN4AALDH1A1MAPTKMT2A | |
| SCHEMBL8945130 | 0.84 | FAAH (0.46) | FAAHMGLLACHESCN4ANQO1 | |
| SCHEMBL8945162 | 0.78 | FAAH (0.41) | FAAHMGLLHIF1AACHESCN4A | |
| SCHEMBL8945016 | 0.77 | FAAH (0.56) | FAAHMGLLACHESCN4ASSTR4 | |
| SCHEMBL8945218 | 0.77 | FAAH (0.44) | FAAHMGLLACHESCN4AALDH1A1 | |
| SCHEMBL8944992 | 0.76 | FAAH (0.44) | FAAHMGLLHIF1ASCN4AL3MBTL1 | |
| SCHEMBL8945017 | 0.76 | FAAH (0.43) | FAAHMGLLACHESCN4AKMT2A | |
| SCHEMBL8945065 | 0.75 | FAAH (0.54) | FAAHMGLLACHESCN4ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |