Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.31 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944994 | 0.90 | HDAC4 (0.34) | HDAC4DHFRCYP3A4CYP2C19 | |
| SCHEMBL8945147 | 0.85 | SKP2 (0.38) | HDAC4CYP3A4SLC6A4ALDH1A1GLA | |
| SCHEMBL8945020 | 0.85 | HDAC4 (0.38) | HDAC4DHFRCYP3A4CYP2C19ATP4A | |
| SCHEMBL8945419 | 0.84 | RXRA (0.37) | HDAC4SLC6A4ALDH1A1GLATSHR | |
| SCHEMBL8468338 | 0.82 | ALDH1A1 (0.38) | HDAC4CYP3A4SLC6A4ALDH1A1TSHR | |
| SCHEMBL16593764 | 0.80 | HDAC4 (0.54) | HDAC4SLC6A4SLC6A2POLBMAPT | |
| SCHEMBL10941078 | 0.78 | DHFR (0.43) | DHFRCYP3A4ATP4AATP4BSLC6A4 | |
| SCHEMBL8945201 | 0.77 | SLC6A4 (0.33) | HDAC4SLC6A4SLC6A2FFAR1CETP | |
| SCHEMBL8945132 | 0.74 | SKP2 (0.38) | HDAC4SLC6A4SLC6A2FFAR1 | |
| SCHEMBL8766914 | 0.74 | ALDH1A1 (0.45) | DHFRCYP3A4ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |