Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944901 | 0.86 | FAAH (0.46) | MAPTFAAHMGLLPOLBKDM4E | |
| SCHEMBL8945100 | 0.86 | FAAH (0.39) | MAPTFAAHMGLLPOLBKDM4E | |
| SCHEMBL8945077 | 0.86 | MAPT (0.43) | MAPTFAAHMGLLTP53POLB | |
| Hydrochloric Acid SCHEMBL8944982 | 0.85 | MAPT (0.42) | MAPTFAAHMGLLTP53POLB | |
| SCHEMBL8944998 | 0.83 | FAAH (0.58) | FAAHMGLLLMNA | |
| Hydrochloric Acid SCHEMBL8945358 | 0.82 | FAAH (0.57) | FAAHMGLLLMNA | |
| SCHEMBL8945126 | 0.75 | FAAH (0.48) | MAPTFAAHMGLLKDM4ETAS1R3 | |
| SCHEMBL5617540 | 0.75 | MAPT (0.44) | MAPTFAAHMGLLTP53POLB | |
| SCHEMBL8945193 | 0.75 | FAAH (0.45) | MAPTFAAHMGLLKDM4ETAS1R3 | |
| SCHEMBL2968296 | 0.75 | MAPT (0.47) | MAPTFAAHMGLLTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |