Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945050 | 0.86 | KCNA5 (0.37) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8945166 | 0.86 | MAPT (0.39) | FAAHMGLLTAS1R3TAS1R1NPC1 | |
| SCHEMBL8944901 | 0.85 | FAAH (0.46) | FAAHMGLLTAS1R3TAS1R1KDM4E | |
| SCHEMBL8944998 | 0.82 | FAAH (0.58) | FAAHMGLLSMN1; SMN2ACHE | |
| Hydrochloric Acid SCHEMBL8945358 | 0.81 | FAAH (0.57) | FAAHMGLLSMN1; SMN2ACHE | |
| SCHEMBL5617796 | 0.76 | FAAH (0.43) | FAAHMGLLNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL6991179 | 0.75 | FAAH (0.43) | FAAHMGLLNPC1RAB9AKDM4E | |
| SCHEMBL8945126 | 0.74 | FAAH (0.48) | FAAHMGLLTAS1R3TAS1R1KDM4E | |
| SCHEMBL8945193 | 0.74 | FAAH (0.45) | FAAHMGLLTAS1R3TAS1R1KDM4E | |
| SCHEMBL8944942 | 0.73 | L3MBTL1 (0.44) | NPC1RAB9ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578627-A | FOR TREATING CEREBRAL CIRCULATORY DISORDER, HEAD INJURY SEQUELAE AND/OR EPILEPSY | TOYAMA CHEMICAL CO., LTD. (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0665226-A1 | NOVEL 1,2-BENZISOXAZOLE DERIVATIVE OR SALT THEREOF, AND BRAIN PROTECTIVE AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |