Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945071 | 0.91 | SLC10A2 (0.33) | HTR6NOS3NOS1NOS2ALDH1A1 | |
| SCHEMBL8945039 | 0.89 | SLC10A2 (0.35) | HTR6GSK3BNOS3NOS1NOS2 | |
| SCHEMBL8945145 | 0.88 | SLC10A2 (0.33) | HTR6GSK3B | |
| SCHEMBL8944930 | 0.87 | KDM1A (0.44) | HTR6GSK3BNOS3NOS1NOS2 | |
| SCHEMBL8945125 | 0.87 | GSK3B (0.34) | HTR6GSK3BALDH1A1 | |
| SCHEMBL8945347 | 0.87 | CYP19A1 (0.33) | HTR6HTR2CHTR2A | |
| SCHEMBL8945247 | 0.87 | CYP19A1 (0.33) | HTR6HTR2CHTR2A | |
| SCHEMBL8945330 | 0.87 | CYP19A1 (0.33) | HTR6HTR2CHTR2A | |
| SCHEMBL8945269 | 0.85 | HTR6 (0.32) | HTR6GSK3B | |
| SCHEMBL8945265 | 0.84 | HTR6 (0.36) | HTR6GSK3BNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |