SCHEMBL8945347

SCHEMBL8945347

CCCCCCC1(Cc2ccc(N)cc2)CCCCC1c1ccccc1C

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.33
SLC10A2 Q12908 2/20 0.32
MMP2 P08253 2/20 0.32
MMP9 P14780 2/20 0.32
MMP8 P22894 2/20 0.32
MMP13 P45452 2/20 0.32
BACE1 P56817 1/20 0.31
BACE2 Q9Y5Z0 1/20 0.31
CETP P11597 2/20 0.31
DRD2 P14416 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
SLC6A4 P31645 1/20 0.31
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945330 1.00 CYP19A1 (0.33) CYP19A1SLC10A2MMP2MMP9MMP8
SCHEMBL8945247 1.00 CYP19A1 (0.33) CYP19A1SLC10A2MMP2MMP9MMP8
SCHEMBL8945145 0.99 SLC10A2 (0.33) CYP19A1SLC10A2MMP2MMP9MMP8
SCHEMBL8945039 0.96 SLC10A2 (0.35) CYP19A1SLC10A2HTR6
SCHEMBL8945071 0.91 SLC10A2 (0.33) SLC10A2HTR6
SCHEMBL8945227 0.87 HTR6 (0.34) HTR2AHTR2CHTR6
SCHEMBL8945308 0.79 KDM1A (0.40) SLC10A2HTR6
SCHEMBL8945087 0.79 SLC10A2 (0.35) CYP19A1SLC10A2HTR6
SCHEMBL8945429 0.78 SLC10A2 (0.32) SLC10A2HTR6
SCHEMBL8945265 0.78 HTR6 (0.36) HTR2AHTR2CHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed