SCHEMBL8945310

SCHEMBL8945310

CCCC1CCC(c2ccc(Cc3ccc(N)cc3)c(F)c2)CC1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.43
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
MEN1 O00255 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
SPHK1 Q9NYA1 1/20 0.33
PANK3 Q9H999 1/20 0.32
RORC P51449 4/20 0.32
ESR2 Q92731 2/20 0.32
TOP2A P11388 1/20 0.32
TOP2B Q02880 1/20 0.32
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944934 0.90 ALDH1A1 (0.33) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945075 0.86 CYP2C9 (0.44) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945090 0.86 CYP2C9 (0.47) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945434 0.85 CYP2C9 (0.43) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945336 0.85 ESR2 (0.37) ALDH1A1PANK3RORCESR2TOP2A
SCHEMBL14274432 0.84 SLC6A4 (0.39) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL7753744 0.83 CYP2C9 (0.56) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8945214 0.82 HTR1D (0.42) ALDH1A1CYP3A4TSHRTDP1
SCHEMBL8945040 0.80 SPHK1 (0.38) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL8765909 0.79 ALDH1A1 (0.31) ALDH1A1TOP2ATOP2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed