Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LOX | P28300 | 3/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945406 | 1.00 | ALDH1A1 (0.59) | ALDH1A1HPGDLOXL2KMT2ATP53 | |
| Safironil SCHEMBL344153 | 0.97 | ALDH1A1 (0.62) | ALDH1A1HPGDKMT2AL3MBTL1KDM4E | |
| Lufironil SCHEMBL344625 | 0.94 | HPGD (0.56) | ALDH1A1HPGDLOXL2KMT2ATP53 | |
| SCHEMBL9404070 | 0.88 | ALDH1A1 (0.57) | ALDH1A1HPGDLOXL2KMT2ATP53 | |
| SCHEMBL9561509 | 0.85 | HPGD (0.58) | ALDH1A1HPGDKMT2ATP53L3MBTL1 | |
| SCHEMBL8842629 | 0.85 | LOXL2 (0.50) | ALDH1A1HPGDLOXL2KMT2ATP53 | |
| SCHEMBL8842613 | 0.84 | TSHR (0.70) | ALDH1A1KMT2ATP53L3MBTL1KDM4E | |
| SCHEMBL5217144 | 0.82 | TP53 (0.47) | ALDH1A1HPGDKMT2ATP53L3MBTL1 | |
| SCHEMBL9561714 | 0.82 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2AL3MBTL1KDM4E | |
| SCHEMBL9561544 | 0.81 | POLB (0.51) | ALDH1A1KMT2AL3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519038-A | ENZYME INHIBITORS SUITABLE AS FIBROSUPPRESSANTS AND IMMUNOSUPPRESSANTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |