Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945334 | 0.89 | POLB (0.54) | POLBKMT2AITGB3ITGA2BMEN1 | |
| SCHEMBL9561769 | 0.85 | KMT2A (0.41) | POLBKMT2AITGB3ITGA2BMEN1 | |
| SCHEMBL15994317 | 0.84 | JMJD7 (0.49) | POLBKMT2AMEN1SMN1; SMN2NAAA | |
| Safironil SCHEMBL344153 | 0.84 | ALDH1A1 (0.62) | KMT2AITGB3ITGA2BMEN1SMN1; SMN2 | |
| SCHEMBL5214396 | 0.83 | KDM5B (0.60) | POLBKDM4E | |
| SCHEMBL14904964 | 0.82 | KMT2A (0.52) | POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8945406 | 0.81 | ALDH1A1 (0.59) | KMT2ASMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8945381 | 0.81 | ALDH1A1 (0.59) | KMT2ASMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL9561509 | 0.80 | HPGD (0.58) | KMT2AITGB3ITGA2BMEN1SMN1; SMN2 | |
| Lufironil SCHEMBL344625 | 0.80 | HPGD (0.56) | KMT2AITGB3ITGA2BMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260323-A | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |