Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1998845 | 1.00 | KDM4E (0.62) | KDM4EPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL6545140 | 1.00 | KDM4E (0.62) | KDM4EPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL9289108 | 0.99 | KDM4E (0.63) | KDM4EPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL374959 | 0.95 | KDM4E (0.68) | KDM4EPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL10395020 | 0.87 | POLB (0.56) | KDM4EPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL10395019 | 0.87 | POLB (0.56) | KDM4EPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL11040105 | 0.87 | KDM4E (0.57) | KDM4EPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL4914902 | 0.86 | KDM4E (0.55) | KDM4EPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL9065653 | 0.86 | KDM4E (0.58) | KDM4EPOLBTDP1ALDH1A1LMNA | |
| SCHEMBL5661958 | 0.85 | KDM4E (0.57) | KDM4EPOLBTDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837967-A | Expandable vinyl aromatic polymeric compositions | 维尔萨利斯股份公司 | 2016-08-10 | — | — | CN | claimed |
| US-5589312-A | RESIN GRAINS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |