SCHEMBL4914902

SCHEMBL4914902

CC(=CC=Cc1ccccc1)C(=O)OCCCO

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.55
POLB P06746 1/20 0.51
ALDH1A1 P00352 5/20 0.47
LMNA P02545 4/20 0.47
TDP1 Q9NUW8 2/20 0.44
GRIK1 P39086 1/20 0.44
HPGD P15428 3/20 0.42
GAA P10253 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GLA P06280 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5406162 0.92 POLB (0.53) KDM4EPOLBALDH1A1LMNATDP1
SCHEMBL10395019 0.90 POLB (0.56) KDM4EPOLBALDH1A1LMNATDP1
SCHEMBL10395020 0.90 POLB (0.56) KDM4EPOLBALDH1A1LMNATDP1
SCHEMBL374959 0.89 KDM4E (0.68) KDM4EPOLBALDH1A1LMNATDP1
SCHEMBL9289108 0.88 KDM4E (0.63) KDM4EPOLBALDH1A1LMNATDP1
SCHEMBL35852 0.87 KDM4E (0.49) KDM4EPOLBALDH1A1LMNATDP1
SCHEMBL1998845 0.86 KDM4E (0.62) KDM4EPOLBALDH1A1LMNATDP1
SCHEMBL8945396 0.86 KDM4E (0.62) KDM4EPOLBALDH1A1LMNATDP1
SCHEMBL6545140 0.86 KDM4E (0.62) KDM4EPOLBALDH1A1LMNATDP1
SCHEMBL28077001 0.83 KDM4E (0.50) KDM4EPOLBALDH1A1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120213996-A1 ALLERGEN-INHIBITING FIBERS SUZUKI TARO (JP) 2012-08-23 US disclosed
US-20080138311-A1 Allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet SUZUKI TARO 2008-06-12 US disclosed
US-20050095222-A1 Allergen inhibitor, allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet SEKISUI CHEMICAL CO., LTD. (JP) 2005-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050095222-A1 Allergen inhibitor, allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet CMA1, HLA-DRB1, ITCH KDM4E 1532/4885POLB 3931/4885ALDH1A1 4512/4885
US-20080138311-A1 Allergen-inhibiting method, allergen-inhibiting fiber and allergen-inhibiting sheet CMA1, HRH2, HLA-DRB1 KDM4E 1396/4885POLB 3883/4885ALDH1A1 4502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.