Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945632 | 0.83 | NQO1 (0.51) | NQO1ELANECTRC | |
| SCHEMBL8945635 | 0.73 | NQO1 (0.41) | NQO1KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL8945626 | 0.72 | NQO1 (0.50) | NQO1KDM4EALDH1A1 | |
| SCHEMBL8945477 | 0.70 | VKORC1 (0.39) | NQO1KDM4EALDH1A1 | |
| SCHEMBL8945587 | 0.70 | L3MBTL1 (0.41) | NQO1KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8945599 | 0.69 | VKORC1 (0.42) | NQO1KDM4E | |
| SCHEMBL9836782 | 0.68 | KMT2A (0.57) | KDM4ENPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL8945281 | 0.67 | LMNA (0.47) | NQO1KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL8945493 | 0.67 | AKR1C3 (0.52) | NQO1KDM4ENPC1ALDH1A1HPGD | |
| SCHEMBL6957985 | 0.66 | NQO1 (0.60) | NQO1KDM4ENPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510375-A | VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |