Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746746 | 0.84 | ALDH1A1 (0.54) | BRD4ALDH1A1LMNAHPGDALOX15 | |
| SCHEMBL8198624 | 0.80 | BRD4 (0.62) | BRD4ALDH1A1LMNAHPGDMAPT | |
| Thiophanate SCHEMBL29398343 | 0.80 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Thiophanate SCHEMBL20842 | 0.80 | ALDH1A1 (0.70) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Thiophanate SCHEMBL10922494 | 0.79 | ALDH1A1 (0.79) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL11694452 | 0.79 | ALDH1A1 (0.79) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| Thiophanate SCHEMBL7449541 | 0.79 | ALDH1A1 (0.68) | ALDH1A1LMNAHPGDALOX15HSD17B10 | |
| SCHEMBL29694632 | 0.79 | BRD4 (0.76) | BRD4ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL1991248 | 0.79 | BRD4 (0.76) | BRD4ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL11835690 | 0.78 | ALDH1A1 (0.62) | ALDH1A1LMNAHPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494887-A | Ring annulated 5-alkoxy-n-aryl[1,2,4]triazolo[1,5-C]-pyrimidine-2-sulfonamide herbicides | DOWELANCO (US) | 1996-02-27 | — | — | US | disclosed |