Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945542 | 0.87 | CNR2 (0.52) | MAPTMEN1KMT2ACNR2GPR55 | |
| SCHEMBL8945436 | 0.81 | VKORC1 (0.55) | MEN1KMT2AKDM4ECNR2NQO1 | |
| SCHEMBL8945707 | 0.79 | NQO1 (0.46) | MAPTCNR2GPR55NQO1POLB | |
| SCHEMBL7379480 | 0.79 | VKORC1 (0.55) | MEN1KMT2AKDM4ECNR2NQO1 | |
| SCHEMBL8945586 | 0.75 | NQO1 (0.58) | MAPTCNR2NQO1POLB | |
| SCHEMBL6952277 | 0.75 | NQO1 (0.54) | KDM4ECNR2NQO1POLB | |
| SCHEMBL8945678 | 0.74 | NQO1 (0.63) | MAPTKDM4ECNR2GPR55NQO1 | |
| SCHEMBL8945339 | 0.74 | NQO1 (0.47) | MAPTCNR2GPR55NQO1POLB | |
| SCHEMBL11477991 | 0.70 | MAOB (0.54) | MAPTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11478429 | 0.69 | ADORA3 (0.48) | MAPTMEN1KMT2AKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510375-A | VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |