Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | BRD2 | P25440 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11477475 | 0.86 | ADORA3 (0.53) | ADORA3ADORA2AADORA1MAOBERAP1 | |
| SCHEMBL11491095 | 0.83 | ERAP1 (0.49) | ADORA3ADORA2AADORA1MAOBERAP1 | |
| SCHEMBL11483271 | 0.83 | MAOB (0.45) | ADORA3ADORA2AADORA1MAOBERAP1 | |
| SCHEMBL11480829 | 0.80 | ABCG2 (0.61) | ADORA3ADORA2AADORA1MAOBERAP1 | |
| SCHEMBL11477991 | 0.80 | MAOB (0.54) | MAOBERAP1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL669375 | 0.77 | MAOB (0.70) | MAOBERAP1GPR35ALDH1A1KDM4E | |
| SCHEMBL29466790 | 0.77 | MAOB (0.70) | MAOBERAP1GPR35ALDH1A1KDM4E | |
| SCHEMBL24865069 | 0.76 | ADORA3 (0.41) | ADORA3ADORA2AADORA1HDAC4HDAC2 | |
| SCHEMBL10372560 | 0.76 | HNF4A (0.49) | ADORA3ADORA2AADORA1HDAC4HDAC2 | |
| SCHEMBL933166 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230850-A | HYPOTENSIVE AGENTS, VASODILATION | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-10-28 | — | — | US | disclosed |