Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12379193 | 0.87 | NPC1 (0.54) | NPC1ALDH1A1KMT2APTK2BLMNA | |
| SCHEMBL8945690 | 0.85 | ALDH1A1 (0.66) | NPC1ALDH1A1KMT2APTK2BLMNA | |
| SCHEMBL2723234 | 0.77 | NPC1 (0.75) | NPC1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14936123 | 0.76 | ALDH1A1 (0.51) | NPC1ALDH1A1KMT2APTK2BLMNA | |
| SCHEMBL9462122 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KMT2APTK2BLMNASMN1; SMN2 | |
| SCHEMBL1549099 | 0.75 | NPC1 (0.72) | NPC1ALDH1A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL25788066 | 0.75 | ALDH1A1 (0.84) | NPC1ALDH1A1KMT2APTK2BLMNA | |
| SCHEMBL6042573 | 0.75 | ALDH1A1 (0.84) | NPC1ALDH1A1KMT2APTK2BLMNA | |
| SCHEMBL7523994 | 0.74 | LMNA (0.67) | ALDH1A1KMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL6043026 | 0.74 | ALDH1A1 (0.76) | NPC1ALDH1A1KMT2APTK2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510375-A | VIRICIDES TREATING INFECTION CAUSED BY HUMAN IMMUNODEFICIENCY VIRUS AND AIDS | WARNER-LAMBERT COMPANY (US) | 1996-04-23 | — | — | US | disclosed |