SCHEMBL6042573

SCHEMBL6042573

COCCOCCOc1ccccc1C(=O)O

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.84
KMT2A Q03164 3/20 0.84
PTK2B Q14289 1/20 0.84
KDM4E B2RXH2 6/20 0.66
LMNA P02545 3/20 0.66
SMN1; SMN2 Q16637 3/20 0.66
HTT P42858 2/20 0.53
MEN1 O00255 2/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
CYP2C9 P11712 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HPGD P15428 3/20 0.50
HSD17B10 Q99714 3/20 0.50
MAPT P10636 1/20 0.50
POLB P06746 1/20 0.49
TSHR P16473 2/20 0.49
ESR1 P03372 1/20 0.49
ITGB3 P05106 1/20 0.49
ITGA2B P08514 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25788066 1.00 ALDH1A1 (0.84) ALDH1A1KMT2APTK2BKDM4ELMNA
SCHEMBL1505142 0.95 ALDH1A1 (0.74) ALDH1A1KMT2APTK2BKDM4ELMNA
SCHEMBL26355092 0.94 ALDH1A1 (0.73) ALDH1A1KMT2APTK2BKDM4ELMNA
SCHEMBL24801375 0.92 ALDH1A1 (1.00) ALDH1A1KMT2APTK2BKDM4ELMNA
SCHEMBL14964190 0.92 ALDH1A1 (1.00) ALDH1A1KMT2APTK2BKDM4ELMNA
SCHEMBL8945690 0.89 ALDH1A1 (0.66) ALDH1A1KMT2APTK2BKDM4ELMNA
SCHEMBL6043026 0.89 ALDH1A1 (0.76) ALDH1A1KMT2APTK2BKDM4ELMNA
SCHEMBL29013661 0.87 ALDH1A1 (0.84) ALDH1A1KMT2APTK2BKDM4ELMNA
SCHEMBL3383338 0.87 ALDH1A1 (0.67) ALDH1A1KMT2APTK2BKDM4ELMNA
SCHEMBL6044048 0.87 ALDH1A1 (0.67) ALDH1A1KMT2APTK2BKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119233964-A Single component delivery system for nucleic acids 宾夕法尼亚大学理事会 2024-12-31 CN disclosed
CN-114466835-B Thermally responsive molecules for controlled heat and light transmission windows and uses thereof 科学与工业研究会 2024-06-04 CN disclosed
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-29 US disclosed
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-06-29 US disclosed
CN-114466835-A Thermally responsive molecules for controlled thermal and optical transmission windows and uses thereof 科学与工业研究会 2022-05-10 CN disclosed
CN-108558701-B Micromolecule AIEE luminescent material with triple stimulus responsiveness and preparation method thereof 湘潭大学 2020-11-03 CN disclosed
US-20060089355-A1 Methods of treating alzheimer's disease using aromatically substituted w-amino-alkanoic acid amides and alkanoic acid diamides ELAN PHARMACEUTICALS, INC. 2006-04-27 US disclosed
WO-2003103652-A1 METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES ELAN PHARMACEUTICALS, INC. (US) 2003-12-18 WO disclosed
US-5925780-A VIRICIDES FOR RETROVIRAL SPECIES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-07-20 US disclosed
US-5728718-A RETROVIRAL PROTEASE INHIBITOR; TREATMENT OF HTLV THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-03-17 US disclosed
US-5641778-A EXHIBIT RENIN-INHIBITING PROPERTIES AND CAN BE USED AS ANTIHYPERTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1997-06-24 US disclosed
EP-0716077-A1 Aromatically substituted omega amino alcanoic acid amides and alcanoic diamides and their use as renine inhibitors CIBA-GEIGY AG (CH) 1996-06-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230205083-A1 SALT COMPOUND, RESIST COMPOSITION AND PATTERNING PROCESS SLC6A9, SLC6A5, REN ALDH1A1 3949/4885KMT2A 2175/4885PTK2B 2390/4885
US-20060089355-A1 Methods of treating alzheimer's disease using aromatically substituted w-amino-alkanoic acid amides and alkanoic acid diamides APP, BACE1, BACE2 ALDH1A1 1039/4885KMT2A 2309/4885PTK2B 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.