Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 6/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945992 | 0.91 | MMP8 (0.37) | MMP8MMP1MMP9MMP13RIPK1 | |
| Hydrochloric Acid SCHEMBL9482605 | 0.75 | SLC6A2 (0.39) | MMP8MMP1MMP9MMP13RECQL | |
| SCHEMBL8761086 | 0.70 | CYP3A4 (0.64) | MMP8MMP1MMP9MMP13ALDH1A1 | |
| SCHEMBL8761288 | 0.68 | SLC6A2 (0.50) | MMP1MMP9MMP13ALDH1A1RECQL | |
| Benzene SCHEMBL9483683 | 0.68 | KCNN4 (0.36) | RIPK1ALDH1A1 | |
| Maleic Acid SCHEMBL9482672 | 0.68 | TAAR1 (0.44) | MMP1MMP9MMP13ALDH1A1RECQL | |
| Fumaric Acid SCHEMBL9482681 | 0.68 | TAAR1 (0.44) | MMP1MMP9MMP13ALDH1A1RECQL | |
| SCHEMBL8945878 | 0.67 | RIPK1 (0.39) | MMP8MMP1MMP9MMP13RIPK1 | |
| SCHEMBL8946105 | 0.66 | RIPK1 (0.38) | MMP8MMP1MMP9MMP13RIPK1 | |
| Fumaric Acid SCHEMBL8760258 | 0.66 | CYP3A4 (0.57) | MMP1MMP9MMP13ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |