Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945998 | 0.89 | RIPK1 (0.40) | RIPK1OPRK1MMP1MMP9MMP13 | |
| SCHEMBL8946105 | 0.87 | RIPK1 (0.38) | RIPK1MMP1MMP9MMP13MMP8 | |
| SCHEMBL8945920 | 0.81 | MMP1 (0.42) | RIPK1OPRK1MMP1MMP9MMP13 | |
| SCHEMBL8945941 | 0.78 | RIPK1 (0.39) | RIPK1OPRK1MMP8OPRM1OPRD1 | |
| SCHEMBL8945899 | 0.78 | OPRK1 (0.41) | RIPK1OPRK1MMP1MMP9MMP13 | |
| SCHEMBL8945836 | 0.75 | OPRK1 (0.41) | RIPK1OPRK1MMP8 | |
| SCHEMBL8945854 | 0.74 | RIPK1 (0.40) | RIPK1OPRK1MMP8OPRM1OPRD1 | |
| SCHEMBL8760252 | 0.73 | TAAR1 (0.44) | — | |
| SCHEMBL8945943 | 0.73 | L3MBTL1 (0.44) | OPRK1 | |
| Hydrochloric Acid SCHEMBL9482849 | 0.72 | TAAR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |