Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945821 | 0.81 | KMT2A (0.51) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8945908 | 0.80 | MEN1 (0.50) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8945929 | 0.78 | SMN1; SMN2 (0.48) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8945870 | 0.78 | MEN1 (0.48) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8945931 | 0.76 | MEN1 (0.49) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8945847 | 0.75 | CYP2C19 (0.50) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL8946107 | 0.74 | MEN1 (0.47) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8945890 | 0.70 | ALOX5 (0.37) | MEN1KMT2AALOX5ALDH1A1OPRD1 | |
| SCHEMBL8945987 | 0.69 | MEN1 (0.46) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9425144 | 0.68 | CETP (0.40) | MEN1KMT2AALDH1A1GLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |