Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945821 | 0.81 | KMT2A (0.51) | CYP2C19CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8945929 | 0.79 | SMN1; SMN2 (0.48) | CYP2C19CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8945908 | 0.76 | MEN1 (0.50) | CYP2C19CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8945883 | 0.75 | MEN1 (0.49) | CYP2C19CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8945931 | 0.75 | MEN1 (0.49) | CYP2C19CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8945870 | 0.74 | MEN1 (0.48) | CYP2C19CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28622173 | 0.73 | ALDH1A1 (0.46) | CYP2C19CYP3A4MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8946107 | 0.73 | MEN1 (0.47) | CYP2C19CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4055323 | 0.69 | TSHR (0.44) | CYP2C19CYP3A4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL41938 | 0.69 | CYP2C19 (0.44) | CYP2C19CYP3A4CYP2C9POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |