Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945911 | 0.82 | ALOX5 (0.36) | ALOX5OPRK1MAPTNR3C1ALDH1A1 | |
| SCHEMBL8945826 | 0.81 | ROCK1 (0.40) | RPS6KB1OPRK1RIPK1 | |
| SCHEMBL8945873 | 0.80 | ALOX5 (0.37) | ALOX5OPRK1NR3C1 | |
| SCHEMBL8945932 | 0.80 | ITGB3 (0.39) | ALDH1A1 | |
| SCHEMBL8945937 | 0.79 | ALOX5 (0.36) | ALOX5RPS6KB1OPRK1MAPTRIPK1 | |
| SCHEMBL8945850 | 0.77 | ALDH1A1 (0.43) | OPRK1NR3C1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8946104 | 0.77 | ALOX5 (0.34) | ALOX5RPS6KB1OPRK1MAPTRIPK1 | |
| SCHEMBL8945990 | 0.71 | ALOX5 (0.36) | ALOX5OPRD1RIPK1NR3C1 | |
| SCHEMBL8945883 | 0.70 | MEN1 (0.49) | ALOX5OPRK1OPRD1ADRB3MEN1 | |
| SCHEMBL8946099 | 0.70 | ALOX5 (0.34) | ALOX5RPS6KB1OPRD1MAPTRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |