SCHEMBL8945922

SCHEMBL8945922

Oc1ccc(Sc2ccccc2)c(O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.47
GAA P10253 2/20 0.43
GFER P55789 1/20 0.43
HSP90AA1 P07900 2/20 0.42
NR1H2 P55055 1/20 0.41
SIRT1 Q96EB6 1/20 0.40
MEN1 O00255 1/20 0.40
USP2 O75604 1/20 0.40
KMT2A Q03164 1/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
BCL2 P10415 1/20 0.40
MCL1 Q07820 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
TYR P14679 1/20 0.39
PDE7A Q13946 2/20 0.38
CA12 O43570 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9645548 0.87 NR1H2 (0.56) ALOX5GAAGFERHSP90AA1NR1H2
SCHEMBL2861898 0.83 HPGD (0.44) ALOX5GAAGFERHSP90AA1NR1H2
SCHEMBL14283890 0.82 HSP90AA1 (0.50) GAAHSP90AA1SIRT1MEN1KMT2A
SCHEMBL562184 0.82 TYR (0.44) ALOX5GAAGFERHSP90AA1NR1H2
SCHEMBL29524489 0.82 TYR (0.44) ALOX5GAAGFERHSP90AA1NR1H2
SCHEMBL29465671 0.80 PDE7A (0.54) HSP90AA1MEN1KMT2AALDH1A1HPGD
SCHEMBL8374426 0.80 ESR2 (0.48) GAANR1H2SIRT1ALDH1A1MAPT
SCHEMBL28424052 0.80 PDE7A (0.54) HSP90AA1MEN1KMT2AALDH1A1HPGD
SCHEMBL5841515 0.80 MAPT (0.48) GAAHSP90AA1SIRT1MEN1KMT2A
SCHEMBL5842928 0.80 LMNA (0.47) GAAHSP90AA1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117186446-A Annular phenolic colloid particles, preparation method thereof and annular carbon colloid particles prepared by using annular phenolic colloid particles 中国科学院化学研究所 2023-12-08 CN claimed
EP-0623341-B1 Use of 4-thioresorcin derivatives in skin whitening cosmetic or dermopharmaceutical compositions OREAL (FR) 1996-10-16 EP claimed
US-5468472-A And containing humectant, surfactant, keratolytic agent, antiinflammatory agent, antioxidant, preservative, fragrance, sunscreen L'OREAL (FR) 1995-11-21 US claimed
CN-117186446-A Annular phenolic colloid particles, preparation method thereof and annular carbon colloid particles prepared by using annular phenolic colloid particles 中国科学院化学研究所 2023-12-08 CN disclosed
US-10844180-B2 Structure of phosphorous-containing functionalized poly(arylene ether), composition containing the same, and copper clad laminate Jiangsu Yoke Technology Co., Ltd (CN) 2020-11-24 US disclosed
US-20200140621-A1 STRUCTURE OF PHOSPHOROUS-CONTAINING FUNCTIONALIZED POLY(ARYLENE ETHER), COMPOSITION CONTAINING THE SAME, AND COPPER CLAD LAMINATE Jiangsu Yoke Technology Co., Ltd (CN) 2020-05-07 US disclosed
US-10563019-B2 Structure of phosphorous-containing functionalized poly(arylene ether) and compositions prepared therefrom Jiangsu Yoke Technology Co., Ltd (CN) 2020-02-18 US disclosed
US-20160130406-A1 STRUCTURE OF PHOSPHOROUS-CONTAINING FUNCTIONALIZED POLY(ARYLENE ETHER) AND COMPOSITIONS PREPARED THEREFROM Jiangsu Yoke Technology Co., Ltd (CN) 2016-05-12 US disclosed
US-5580702-A COMPRISING A PHOTOSENSITIVE ACID-GENERATING COMPOUND AND A COPOLYMER OF P-HYDROXYSTYRENE AND AN ESTER OF P-CARBOXYMETHOXYSTYRENE; NONTOXIC; STEEP WALLS; HIGH SPEED; SEMICONDUCTORS KABUSHIKI KAISHA TOSHIBA (JP) 1996-12-03 US disclosed
US-5468472-A And containing humectant, surfactant, keratolytic agent, antiinflammatory agent, antioxidant, preservative, fragrance, sunscreen L'OREAL (FR) 1995-11-21 US disclosed
US-5403695-A Photolithography; high resolution; semiconductors KABUSHIKI KAISHA TOSHIBA (JP) 1995-04-04 US disclosed