SCHEMBL5842928

SCHEMBL5842928

COc1ccc(Sc2ccccc2)c(O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
HPGD P15428 3/20 0.47
ALDH1A1 P00352 3/20 0.47
CYP1A2 P05177 3/20 0.47
PGR P06401 2/20 0.47
SLC6A2 P23975 2/20 0.47
CYP2C19 P33261 2/20 0.47
MAPK1 P28482 2/20 0.47
CYP2D6 P10635 1/20 0.47
PDE4A P27815 1/20 0.47
HRH1 P35367 1/20 0.47
HTT P42858 1/20 0.47
SLC6A3 Q01959 1/20 0.47
PDE4D Q08499 1/20 0.47
CYP3A4 P08684 2/20 0.45
ADORA3 P0DMS8 1/20 0.45
AR P10275 1/20 0.45
CHRM1 P11229 1/20 0.45
ALOX15 P16050 1/20 0.45
TBXA2R P21731 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29083009 0.84 CYP1A2 (0.45) LMNAALDH1A1CYP1A2SLC6A2SLC6A3
SCHEMBL6512960 0.81 CYP1A2 (0.42) LMNAALDH1A1CYP1A2SLC6A2SLC6A3
SCHEMBL8945922 0.80 ALOX5 (0.47) HPGDALDH1A1MAPTMEN1KMT2A
SCHEMBL2970197 0.79 SLC6A2 (0.57) LMNAHPGDALDH1A1CYP1A2SLC6A2
SCHEMBL6516187 0.77 ALDH1A1 (0.53) LMNAHPGDALDH1A1CYP1A2PGR
SCHEMBL2887157 0.77 PTGIR (0.50) LMNAALDH1A1CYP1A2MAPK1AR
SCHEMBL5841515 0.77 MAPT (0.48) LMNAHPGDALDH1A1SLC6A2CHRM1
SCHEMBL6516678 0.76 CYP1A2 (0.41) LMNAALDH1A1CYP1A2MEN1KMT2A
SCHEMBL11580822 0.76 MAOB (0.48) HPGDALDH1A1CYP2C19MAPK1CYP2D6
SCHEMBL16495093 0.76 ERN1 (0.50) LMNAALDH1A1CYP1A2CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6984716-B2 Phosphorus-containing compound CHANG CHUN PLASTICS CO., LTD. (TW) 2006-01-10 US disclosed
US-20040077821-A1 Flame retarding resin composition CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-22 US disclosed
US-20040077825-A1 Phosphorus-containing compound CHANG CHUN PLASTICS CO., LTD. (TW) 2004-04-22 US disclosed