Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945922 | 0.87 | ALOX5 (0.47) | NR1H2HSP90AA1TSHRTYRCA2 | |
| SCHEMBL29524489 | 0.85 | TYR (0.44) | NR1H2HSP90AA1CYP3A4ALOX15HIF1A | |
| SCHEMBL562184 | 0.85 | TYR (0.44) | NR1H2HSP90AA1CYP3A4ALOX15HIF1A | |
| SCHEMBL1561810 | 0.79 | ALOX15 (0.41) | NR1H2HSP90AA1CYP3A4ALOX15HIF1A | |
| SCHEMBL1454650 | 0.78 | NR1H2 (0.52) | NR1H2HSP90AA1CYP3A4ALOX15HIF1A | |
| SCHEMBL11092955 | 0.78 | NR1H2 (0.52) | NR1H2CYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL5399446 | 0.77 | NR1H2 (0.56) | NR1H2HSP90AA1CYP3A4ALOX15HIF1A | |
| SCHEMBL11728749 | 0.77 | ALDH1A1 (0.50) | NR1H2HSP90AA1CYP3A4ALOX15HIF1A | |
| SCHEMBL21938771 | 0.77 | TYR (0.38) | NR1H2CYP3A4ALOX15HIF1AHSD17B10 | |
| SCHEMBL8756504 | 0.77 | PTGS2 (0.60) | CYP3A4ALOX15HIF1AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257011-B1 | PERMEATION MODIFIED ASYMMETRIC GAS SEPARATION MEMBRANES HAVING GRADED DENSITY SKINS | PERMEA, Inc. (US) | 1992-10-07 | — | — | EP | disclosed |
| US-4728346-A | PERMSELECTIVITY | PERMEA INC. (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0257011-A2 | Permeation modified asymmetric gas separation membranes having graded density skins | PERMEA, Inc. (US) | 1988-02-24 | — | — | EP | disclosed |
| US-4575385-A | POLYSULFONES CONTACTED WITH BENZENE COMPOUND | MONSANTO COMPANY (US) | 1986-03-11 | — | — | US | disclosed |