SCHEMBL8946061

SCHEMBL8946061

CNC(=O)N(C)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
PKM P14618 1/20 0.54
ROCK2 O75116 1/20 0.50
KDM4E B2RXH2 2/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 3/20 0.47
POLB P06746 1/20 0.47
FAAH O00519 1/20 0.45
PHGDH O43175 1/20 0.45
MGLL Q99685 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MLYCD O95822 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137254 1.00 LMNA (0.59) LMNAL3MBTL1PKMROCK2KDM4E
SCHEMBL9408595 0.89 ROCK2 (0.59) LMNAL3MBTL1PKMROCK2KDM4E
SCHEMBL8905438 0.88 ROCK2 (0.60) LMNAL3MBTL1PKMROCK2KDM4E
SCHEMBL11178753 0.84 LMNA (0.52) LMNAL3MBTL1PKMKDM4ENPC1
SCHEMBL11039869 0.83 LMNA (0.42) LMNAL3MBTL1PKMROCK2KDM4E
SCHEMBL2433724 0.82 ROCK2 (0.50) LMNAL3MBTL1ROCK2NPC1RAB9A
SCHEMBL5255044 0.81 PKM (0.53) LMNAL3MBTL1PKMKDM4ENPC1
SCHEMBL5814273 0.81 ROCK2 (0.53) LMNAL3MBTL1ROCK2KDM4ERAB9A
SCHEMBL9018864 0.81 PKM (0.53) LMNAL3MBTL1PKMKDM4ENPC1
SCHEMBL11554950 0.81 PKM (0.53) LMNAL3MBTL1PKMKDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5573898-A PYRROLOAZOLE CYAN DYE-FORMING COUPLER, WATERPROOF RESIN COATING LAYERS, WHITE PIGMENT FUJI PHOTO FILM CO., LTD. (JP) 1996-11-12 US disclosed
US-5512425-A SMOOTHNESS, GLOSSINESS; WHITE PIGMENT IN POLYESTER FOR REFLECTION FUJI PHOTO FILM CO., LTD. (JP) 1996-04-30 US disclosed