Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9617160 | 0.75 | PRCP (0.47) | TRPA1RAB9AADRA2ACYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL9582716 | 0.74 | PRCP (0.46) | TRPA1RAB9AMEN1KMT2ANOS3 | |
| SCHEMBL13620740 | 0.71 | TRPA1 (0.38) | TSHRTRPA1RAB9ACYP2D6MEN1 | |
| SCHEMBL30358244 | 0.71 | TRPA1 (0.38) | TSHRTRPA1RAB9ACYP2D6MEN1 | |
| SCHEMBL20404734 | 0.71 | TRPA1 (0.38) | TSHRTRPA1RAB9ACYP2D6MEN1 | |
| SCHEMBL8945950 | 0.69 | NOS2 (0.40) | TRPA1MEN1KMT2ANOS3NOS2 | |
| SCHEMBL21065477 | 0.68 | TRPA1 (0.36) | TRPA1RAB9ACYP2D6MEN1RECQL | |
| SCHEMBL840754 | 0.67 | NOS3 (0.47) | TSHRTRPA1RAB9ACYP2D6MEN1 | |
| SCHEMBL16422215 | 0.67 | NOS3 (0.35) | NOS3NOS2NOS1HTR2AHTR2C | |
| SCHEMBL21767243 | 0.66 | TSHR (0.50) | TSHRADRA2ABRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |