Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946019 | 0.90 | MEN1 (0.32) | MEN1NPC1GAARAB9AKMT2A | |
| SCHEMBL8946076 | 0.87 | TDP1 (0.35) | SLC6A4ALOX5 | |
| SCHEMBL8946111 | 0.86 | CYP3A4 (0.39) | SLC6A4ALOX5 | |
| SCHEMBL8946168 | 0.85 | SLC6A2 (0.40) | SLC6A2SLC6A4ALOX5 | |
| Hydrochloric Acid SCHEMBL8946071 | 0.85 | CYP3A4 (0.38) | GAAKMT2A | |
| SCHEMBL8945857 | 0.85 | ALDH1A1 (0.32) | ALOX5 | |
| SCHEMBL8946001 | 0.84 | ALDH1A1 (0.34) | MEN1GAAKMT2ASLC6A2SLC6A4 | |
| SCHEMBL8946175 | 0.82 | MEN1 (0.34) | MEN1GAAKMT2A | |
| SCHEMBL8946017 | 0.81 | ALOX5 (0.33) | KMT2AALOX5MAPK8 | |
| SCHEMBL8945970 | 0.80 | CYP3A4 (0.35) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5292760-A | 4-heteroaryl-1,3-benzodiazepines and 2-substituted-α-(heteroaryl)benzeneethanamines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-08 | — | — | US | disclosed |