Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9001661 | 0.78 | ALDH1A1 (0.42) | SIGMAR1ALDH1A1TAAR1SLC18A2 | |
| Hydrochloric Acid SCHEMBL9001659 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2ASIGMAR1ALDH1A1TAAR1 | |
| Hydrochloric Acid SCHEMBL9582763 | 0.76 | ALDH1A1 (0.41) | MEN1KMT2ASIGMAR1ALDH1A1TAAR1 | |
| SCHEMBL8946094 | 0.75 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL9582838 | 0.71 | CYP3A4 (0.38) | ALDH1A1TAAR1 | |
| SCHEMBL10565227 | 0.71 | GAA (0.38) | MAPTALDH1A1 | |
| SCHEMBL9583335 | 0.71 | CYP2D6 (0.35) | MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9582409 | 0.70 | CYP3A4 (0.41) | ALDH1A1TAAR1 | |
| SCHEMBL9583350 | 0.70 | ALDH1A1 (0.37) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9582500 | 0.70 | CYP2D6 (0.34) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5292760-A | 4-heteroaryl-1,3-benzodiazepines and 2-substituted-α-(heteroaryl)benzeneethanamines | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1994-03-08 | — | — | US | disclosed |