Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119395 | 0.96 | CA2 (0.68) | CA2KDM4EATMPOLBNPC1 | |
| SCHEMBL29997296 | 0.96 | CA2 (0.68) | CA2KDM4EATMPOLBNPC1 | |
| SCHEMBL28170408 | 0.96 | CA2 (0.68) | CA2KDM4EATMPOLBNPC1 | |
| Methyl Alcohol SCHEMBL28203224 | 0.94 | CA2 (0.65) | CA2KDM4EATMPOLBNPC1 | |
| Methane SCHEMBL7067208 | 0.94 | CA2 (0.65) | CA2KDM4EATMPOLBNPC1 | |
| SCHEMBL21328356 | 0.88 | CA2 (0.59) | CA2KDM4EATMPOLBNPC1 | |
| 1,4-Dimethoxybenzene SCHEMBL28240783 | 0.88 | LMNA (0.61) | CA2KDM4EATMPOLBNPC1 | |
| SCHEMBL21328337 | 0.88 | CA2 (0.57) | CA2KDM4EATMPOLBNPC1 | |
| SCHEMBL15170032 | 0.88 | TTR (0.61) | CA2KDM4EATMPOLBNPC1 | |
| Acetic Acid SCHEMBL11795359 | 0.86 | LDHA (0.62) | CA2KDM4EATMPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106176627-B | Method for preparing polydatin resveratrol and emodin | 湖南鑫利生物科技有限公司 | 2018-10-30 | — | — | CN | claimed |
| CN-105709238-B | Embed the peanut protein nano particle and preparation method thereof of resveratrol | 中国农业科学院农产品加工研究所 | 2018-08-17 | — | — | CN | claimed |
| CN-106176627-A | Method for preparing polydatin resveratrol and emodin | 湖南鑫利生物科技有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-109157508-A | A kind of resveratrol nanosuspension and preparation method thereof | 沈阳药科大学 | 2019-01-08 | — | — | CN | disclosed |
| CN-106176627-B | Method for preparing polydatin resveratrol and emodin | 湖南鑫利生物科技有限公司 | 2018-10-30 | — | — | CN | disclosed |
| CN-108403662-A | Trishydroxymethylaminomethane modified corn alcohol soluble protein function drug bearing microsphere and preparation method | 华南理工大学 | 2018-08-17 | — | — | CN | disclosed |
| US-5549789-A | MIXING WOOD PULP WITH POLYOXOMETALLATE SOLUTION, HEATING IN PRESENCE OF GASEOUS OXIDANT TO DEGRADE DISSOLVED LIGNIN AND POLYSACCHARIDE FRAGMENTS TO VOLATILE ORGANIC COMPOUNDS AND WATER | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1996-08-27 | — | — | US | disclosed |