Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 9/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FSHR | P23945 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946372 | 1.00 | MEN1 (0.49) | MEN1KMT2AADRB2NPSR1NOTUM | |
| SCHEMBL8946367 | 1.00 | MEN1 (0.49) | MEN1KMT2AADRB2NPSR1NOTUM | |
| SCHEMBL8946465 | 0.86 | MAPT (0.42) | MEN1KMT2AADRB2NPSR1NOTUM | |
| SCHEMBL8946472 | 0.86 | MAPT (0.42) | MEN1KMT2AADRB2NPSR1NOTUM | |
| SCHEMBL8946480 | 0.86 | MAPT (0.42) | MEN1KMT2AADRB2NPSR1NOTUM | |
| SCHEMBL9018953 | 0.83 | MEN1 (0.38) | MEN1KMT2AADRB2NPSR1NOTUM | |
| SCHEMBL8946924 | 0.83 | MEN1 (0.38) | MEN1KMT2AADRB2NPSR1NOTUM | |
| SCHEMBL9018952 | 0.83 | MEN1 (0.38) | MEN1KMT2AADRB2NPSR1NOTUM | |
| SCHEMBL8946907 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2ANOTUMLMNAGAA | |
| SCHEMBL8946917 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2ANOTUMLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |