Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | FSHR | P23945 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946924 | 1.00 | MEN1 (0.38) | MEN1KMT2AADRB2NPSR1HSP90AA1 | |
| SCHEMBL9018953 | 1.00 | MEN1 (0.38) | MEN1KMT2AADRB2NPSR1HSP90AA1 | |
| SCHEMBL8946472 | 0.84 | MAPT (0.42) | MEN1KMT2AADRB2NPSR1FSHR | |
| SCHEMBL8946480 | 0.84 | MAPT (0.42) | MEN1KMT2AADRB2NPSR1FSHR | |
| SCHEMBL8946465 | 0.84 | MAPT (0.42) | MEN1KMT2AADRB2NPSR1FSHR | |
| SCHEMBL8946379 | 0.83 | MEN1 (0.49) | MEN1KMT2AADRB2NPSR1FSHR | |
| SCHEMBL8946367 | 0.83 | MEN1 (0.49) | MEN1KMT2AADRB2NPSR1FSHR | |
| SCHEMBL8946372 | 0.83 | MEN1 (0.49) | MEN1KMT2AADRB2NPSR1FSHR | |
| SCHEMBL26079157 | 0.70 | PDK1 (0.37) | MEN1KMT2AHSP90AA1HSP90AB1FSHR | |
| SCHEMBL8946416 | 0.66 | HPGD (0.44) | MEN1KMT2AHSP90AA1HSP90AB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |
| WO-1990015799-A1 | INDENOINDOLE COMPOUNDS II | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |