Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GRK6 | P43250 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946620 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL8946628 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL8946294 | 0.75 | MAPT (0.50) | ALDH1A1MAPTKMT2AGAAKDM4E | |
| SCHEMBL277613 | 0.75 | MAPT (0.50) | ALDH1A1MAPTKMT2AGAAKDM4E | |
| SCHEMBL8946291 | 0.75 | MAPT (0.50) | ALDH1A1MAPTKMT2AGAAKDM4E | |
| SCHEMBL8946559 | 0.73 | MAPT (0.36) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL8946557 | 0.73 | MAPT (0.36) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL8946552 | 0.73 | MAPT (0.36) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL8946687 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8946675 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | claimed |
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |