Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | EIF4E | P06730 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946524 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KMT2ANR4A2KDM4EPOLB | |
| SCHEMBL8946514 | 0.80 | KMT2A (0.54) | ALDH1A1KMT2AKDM4EHPGDLMNA | |
| SCHEMBL8946541 | 0.78 | CNR1 (0.45) | ALDH1A1KMT2APOLBNPC1RAB9A | |
| SCHEMBL10900818 | 0.77 | ALDH1A1 (0.64) | ALDH1A1KMT2ASMOKDM4ESMN1; SMN2 | |
| SCHEMBL8946509 | 0.77 | L3MBTL1 (0.60) | ALDH1A1KMT2AKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL12978561 | 0.75 | RXFP1 (0.42) | ALDH1A1KMT2ASMOKDM4EPPARA | |
| SCHEMBL15467864 | 0.74 | KDM4E (0.66) | ALDH1A1KMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL17964400 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL5189312 | 0.74 | CNR1 (0.48) | ALDH1A1KMT2ANR4A2RXRARXRB | |
| SCHEMBL6206542 | 0.73 | KDM4E (0.65) | ALDH1A1KMT2AKDM4ESMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |