Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10634867 | 0.82 | DHODH (0.48) | DHODHKMT2AALDH1A1POLBLMNA | |
| SCHEMBL10634946 | 0.82 | DHODH (0.48) | DHODHKMT2AALDH1A1POLBLMNA | |
| Hydrochloric Acid SCHEMBL10630475 | 0.81 | DHODH (0.47) | DHODHALDH1A1POLBCAMKK1CAMKK2 | |
| SCHEMBL8946636 | 0.78 | ALDH1A1 (0.54) | DHODHKMT2AALDH1A1POLBLMNA | |
| SCHEMBL30408412 | 0.76 | CAMKK2 (0.44) | DHODHKMT2APOLBLMNAHTT | |
| SCHEMBL8946514 | 0.74 | KMT2A (0.54) | CNR1DHODHKMT2AALDH1A1LMNA | |
| SCHEMBL8823085 | 0.73 | BTK (0.48) | CNR1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL27429743 | 0.72 | LMNA (0.37) | CNR1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL8946733 | 0.71 | LPAR1 (0.46) | CNR1 | |
| SCHEMBL8946489 | 0.71 | PYGL (0.46) | CNR1KMT2ANPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |