Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946618 | 0.91 | L3MBTL1 (0.51) | LPAR1L3MBTL1NTRK1LMNAKMT2A | |
| SCHEMBL8946713 | 0.86 | L3MBTL1 (0.41) | L3MBTL1S1PR4NTRK1 | |
| SCHEMBL8946456 | 0.86 | LPAR1 (0.50) | LPAR1L3MBTL1P2RY1S1PR4S1PR5 | |
| SCHEMBL8946420 | 0.86 | L3MBTL1 (0.47) | LPAR1L3MBTL1NTRK1 | |
| SCHEMBL8946571 | 0.84 | LPAR1 (0.50) | LPAR1NTRK1LMNAKMT2A | |
| SCHEMBL8946668 | 0.84 | LPAR1 (0.47) | LPAR1P2RY1NTRK1LMNAKMT2A | |
| SCHEMBL8946359 | 0.84 | NTRK1 (0.53) | LPAR1NTRK1KMT2A | |
| SCHEMBL8946569 | 0.82 | LPAR1 (0.46) | LPAR1P2RY1NTRK1LMNAKMT2A | |
| SCHEMBL8946725 | 0.81 | NTRK1 (0.50) | LPAR1P2RY1NTRK1LMNAKMT2A | |
| SCHEMBL8946592 | 0.80 | LPAR1 (0.47) | LPAR1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |