Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.44 |
| ▸ | PYGL | P06737 | 7/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946618 | 0.94 | L3MBTL1 (0.51) | L3MBTL1NTRK1NTRK3LPAR1NTRK2 | |
| SCHEMBL8946617 | 0.92 | L3MBTL1 (0.53) | L3MBTL1NTRK1PYGLNTRK3NTRK2 | |
| SCHEMBL8946564 | 0.89 | NTRK1 (0.48) | NTRK1NTRK3LPAR1NTRK2 | |
| SCHEMBL8946585 | 0.87 | KDR (0.40) | L3MBTL1PYGLCXCL8 | |
| SCHEMBL8946504 | 0.86 | L3MBTL1 (0.47) | L3MBTL1NTRK1PYGLNTRK3NTRK2 | |
| SCHEMBL8946589 | 0.86 | L3MBTL1 (0.49) | L3MBTL1NTRK1PYGLNTRK3 | |
| SCHEMBL8946655 | 0.86 | LPAR1 (0.46) | L3MBTL1NTRK1LPAR1 | |
| SCHEMBL8946456 | 0.85 | LPAR1 (0.50) | L3MBTL1NTRK1LPAR1 | |
| SCHEMBL8946728 | 0.84 | L3MBTL1 (0.51) | L3MBTL1NTRK1PYGLNTRK3NTRK2 | |
| SCHEMBL8946455 | 0.84 | NTRK1 (0.56) | NTRK1NTRK3LPAR1NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |