Glycerin

Glycerin

SCHEMBL8946729

CCCCOCC(=O)O.OCC(O)CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.50
EPHX2 P34913 1/20 0.44
CES2 O00748 2/20 0.44
PLA2G2C Q5R387 1/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 2/20 0.41
DUSP3 P51452 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 1/20 0.41
PLA2G4B P0C869 2/20 0.39
GPR84 Q9NQS5 4/20 0.39
ALDH1A1 P00352 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Glycol SCHEMBL3738772 0.89 EPHX2 (0.44) USP2EPHX2CES2PLA2G2CTSHR
Alcohol SCHEMBL7530020 0.86 CES2 (0.52) EPHX2CES2TSHRMEN1KMT2A
SCHEMBL24207 0.86
Glycerin SCHEMBL4324599 0.85 USP2 (0.53) USP2CES2PLA2G2CTSHRKDM4E
Ethylene Glycol SCHEMBL3734775 0.84 TSHR (0.54) EPHX2CES2TSHRMEN1KMT2A
SCHEMBL21295324 0.84 CES2 (0.54) EPHX2CES2TSHRMEN1KMT2A
Hydrochloric Acid SCHEMBL1375034 0.84 CES2 (0.54) EPHX2CES2TSHRMEN1KMT2A
Calcium SCHEMBL30605676 0.84 CES2 (0.54) EPHX2CES2TSHRMEN1KMT2A
1,4-Butanediol SCHEMBL3742680 0.82 TSHR (0.52) EPHX2CES2TSHRMEN1KMT2A
Alcohol SCHEMBL8897153 0.82 TSHR (0.52) EPHX2CES2TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545349-A Bleaching composition KAO CORPORATION (JP) 1996-08-13 US disclosed
EP-0447553-B1 BLEACHING COMPOSITION KAO CORP (JP) 1996-06-12 EP disclosed