Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PYGL | P06737 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946489 | 0.86 | PYGL (0.46) | TAS1R3TAS1R1MAPK14PYGLCYP2C9 | |
| SCHEMBL8946406 | 0.83 | LPAR1 (0.47) | LPAR1 | |
| SCHEMBL8946582 | 0.81 | LPAR1 (0.50) | LPAR1 | |
| SCHEMBL8823127 | 0.81 | LPAR1 (0.38) | LPAR1TAS1R3TAS1R1CNR1 | |
| SCHEMBL8946359 | 0.76 | NTRK1 (0.53) | LPAR1 | |
| SCHEMBL8946668 | 0.76 | LPAR1 (0.47) | LPAR1 | |
| SCHEMBL8946495 | 0.76 | MEN1 (0.42) | LPAR1CNR1 | |
| SCHEMBL8946794 | 0.74 | LPAR1 (0.45) | LPAR1 | |
| SCHEMBL8946575 | 0.74 | MEN1 (0.43) | LPAR1CNR1 | |
| SCHEMBL8946569 | 0.74 | LPAR1 (0.46) | LPAR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |