Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946575 | 0.99 | MEN1 (0.43) | MEN1KMT2ATDP1LPAR1CNR1 | |
| SCHEMBL8946790 | 0.92 | CDK9 (0.42) | LPAR1MAPTPTPN11 | |
| SCHEMBL8946722 | 0.91 | PIK3CA (0.44) | TDP1LPAR1MAPTALDH1A1PTPN11 | |
| SCHEMBL8946727 | 0.87 | LMNA (0.43) | MEN1KMT2ACNR1LMNAMAPT | |
| SCHEMBL8946528 | 0.86 | LMNA (0.41) | CNR1LMNAMAPTKCNQ2ALDH1A1 | |
| SCHEMBL8946359 | 0.82 | NTRK1 (0.53) | KMT2ALPAR1 | |
| SCHEMBL8946668 | 0.82 | LPAR1 (0.47) | KMT2ALPAR1LMNA | |
| SCHEMBL8946569 | 0.81 | LPAR1 (0.46) | KMT2ALPAR1LMNA | |
| SCHEMBL8823094 | 0.80 | TDP1 (0.43) | MEN1KMT2ATDP1LPAR1CNR1 | |
| SCHEMBL8946618 | 0.80 | L3MBTL1 (0.51) | KMT2ALPAR1CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500424-A | ENZYME INHIBITORS | NIHON NOHYAKU CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| EP-0638557-A1 | N-phenylpyri(mi)dine-N'-phenyl-urea derivatives, their preparation and their use as ACAT inhibitors | NIHON NOHYAKU CO., LTD. (JP) | 1995-02-15 | — | — | EP | disclosed |