Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946738 | 1.00 | HTR2A (0.33) | HTR2AHTTMAOAMEN1ALDH1A1 | |
| SCHEMBL8946736 | 1.00 | HTR2A (0.33) | HTR2AHTTMAOAMEN1ALDH1A1 | |
| SCHEMBL8946399 | 0.77 | S100B (0.35) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL9018962 | 0.70 | ATM (0.33) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8946658 | 0.70 | ATM (0.33) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8946284 | 0.70 | HTR2A (0.39) | HTR2AHTTMAOAMEN1ALDH1A1 | |
| SCHEMBL8946281 | 0.70 | HTR2A (0.39) | HTR2AHTTMAOAMEN1ALDH1A1 | |
| SCHEMBL8946289 | 0.70 | HTR2A (0.39) | HTR2AHTTMAOAMEN1ALDH1A1 | |
| SCHEMBL8946663 | 0.70 | ATM (0.33) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8946756 | 0.70 | HTR2A (0.37) | HTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| EP-0409410-B1 | Indenoindole compounds | UNIV BATH (GB) | 1996-03-20 | — | — | EP | disclosed |
| EP-0409410-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1991-01-23 | — | — | EP | disclosed |
| WO-1990015799-A1 | INDENOINDOLE COMPOUNDS II | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |